# 107 - Distilling Decades of MedTech Data, Generative AI, and Doing Without Tribal Knowledge with Michelle Wu

- Show: [Let's Combinate](https://hardwarepodcasts.com/podcast/lets-combinate)
- Published: 2023-10-25
- Length: 32m
- Page: https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn
- Listen: https://podcasters.spotify.com/pod/show/letscombinate/episodes/107---Distilling-Decades-of-MedTech-Data--Generative-AI--and-Doing-Without-Tribal-Knowledge-with-Michelle-Wu-e2avlac

## Summary

Michelle Wu, CEO and Founder of NyquistData, explains how her company uses generative AI to distill decades of MedTech data, removing the 'tribal knowledge' barrier for quality and regulatory professionals. She details the distinction between pre-trained models and fine-tuned algorithms, emphasizing that Nyquist’s data is validated and specific to FDA and global medical device regulations, unlike generic models like OpenAI. Wu discusses the challenge of changing organizational culture and overcoming skepticism in life sciences, highlighting features like the 'Device Explorer' and 'Data Writer' that democratize access to complex regulatory insights.

## Chapters

- [0:00](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=0) Introduction: Subbi Seday and Michelle Wu on NyquistData
- [2:30](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=150) Partnering with Quality and Regulatory Teams
- [4:22](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=262) Design Thinking and Understanding User Goals
- [7:09](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=429) Industry Skepticism and Change Management
- [9:17](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=557) Generative AI vs. Traditional AI Outputs
- [11:16](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=676) Nyquist Features: Data Writer and Device Explorer
- [14:31](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=871) Google BART and the Google Accelerator
- [16:25](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=985) Pre-trained Models, Fine-tuning, and Validation
- [23:20](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=1400) Customer Dreams, Fears, and Future Regulation
- [27:11](https://hardwarepodcasts.com/podcast/lets-combinate/2023-10-25-107-distilling-decades-of-medtech-data-generative-ai-and-doing-without-tribal-kn#t=1631) Product Roadmap and Responsible AI Security

## Topics

- [AI & machine learning](https://hardwarepodcasts.com/topic/ai-and-machine-learning)
- [Quality & yield](https://hardwarepodcasts.com/topic/quality-and-yield)
- [Validation & product-market fit](https://hardwarepodcasts.com/topic/validation-and-product-market-fit)
- [Security & privacy](https://hardwarepodcasts.com/topic/security-and-privacy)

## Most relevant to

early-stage companies

## Mentioned

- NyquistData (company)
- Nyquist, AI (product)
- Anora.ai (company)
- Waveall Inc. (company)
- Boston Consulting Group (company)
- Open AI (company)
- Google BART (tool)
- Vertex AI (tool)
- Deep Mind (company)
- Google Accelerator (other)
- ChatGPT (product)
- FDA (other)
- Device Explorer (product)
- Data Writer (product)

## Related episodes from other shows

- [#439: MedTech AI Trends 2025: Scaling Regulatory Intelligence with Michelle Wu](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2025-12-29-439-medtech-ai-trends-2025-scaling-regulatory-intelligence-with-michelle-wu) (Global Medical Device Podcast)
- [#345: Using AI In MedTech](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2023-11-22-345-using-ai-in-medtech) (Global Medical Device Podcast)
- [#443: Generative AI in MedTech: Quality, Risks, and the Autonomy Scale with Ashkon Rasooli](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2026-01-26-443-generative-ai-in-medtech-quality-risks-and-the-autonomy-scale-with-ashkon-ra) (Global Medical Device Podcast)
- [#460: FDA AI Regulations: Master the QA/RA Skills to Stay Ahead](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2026-05-18-460-fda-ai-regulations-master-the-qa-ra-skills-to-stay-ahead) (Global Medical Device Podcast)
- [#353: How Artificial Intelligence is Impacting the MedTech Industry](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2024-01-30-353-how-artificial-intelligence-is-impacting-the-medtech-industry) (Global Medical Device Podcast)

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