# 048 - "Materials" with Hsinjin Yang

- Show: [Let's Combinate](https://hardwarepodcasts.com/podcast/lets-combinate)
- Published: 2022-08-31
- Length: 34m
- Page: https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang
- Listen: https://podcasters.spotify.com/pod/show/letscombinate/episodes/048---Materials-with-Hsinjin-Yang-e1maqb5

## Summary

Dr. Hsinjin Yang of Pioneer Scientific Solutions, a materials engineer with over 30 years of experience at companies like Baxter, UL, and Pfizer, explains the four major factors for selecting materials for biomedical applications: performance, quality, safety, and commercialization. He details how existing polymers like PP and PE are modified through blending or new chemistry to meet specific mechanical, thermal, and biocompatibility requirements for combination products. The discussion covers critical testing methods such as DSC for mixing homogeneity, E&L for sterilization byproducts, and accelerated aging studies to predict shelf life under various radiation and gas sterilization conditions.

## Chapters

- [0:00](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=0) Introduction: Dr. Hsinjin Yang and Pioneer Scientific Solutions
- [1:45](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=105) Material Development: Blending vs. New Chemistry
- [7:48](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=468) Testing Mixing Homogeneity with DSC and Tg
- [9:34](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=574) Mechanical Properties: Tensile, Impact, and Compression
- [11:49](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=709) Biocompatibility, Extractables/Leachables, and Sterilization
- [16:42](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=1002) Processing Grades and Gamma Stabilizers
- [23:10](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=1390) Shelf Life Prediction and Accelerated Aging
- [29:19](https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang#t=1759) Summary: The Four Major Factors for Material Selection

## Topics

- [Materials & manufacturing processes](https://hardwarepodcasts.com/topic/materials-and-processes)
- [Certification & compliance](https://hardwarepodcasts.com/topic/certification-and-compliance)
- [Prototyping & iteration](https://hardwarepodcasts.com/topic/prototyping)

## Most relevant to

established companies

## Mentioned

- Pioneer Scientific Solutions (company)
- Baxter (company)
- UL (company)
- Pfizer (company)
- Eastman (company)
- Dow (company)

## Related episodes from other shows

- [Essentials of Sterilization for Med Device Professionals](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2023-01-26-essentials-of-sterilization-for-med-device-professionals) (Global Medical Device Podcast)
- [#453: Sustainable Material Selection in MedTech with Lucas Pianegonda](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2026-03-30-453-sustainable-material-selection-in-medtech-with-lucas-pianegonda) (Global Medical Device Podcast)
- [#446: The Hidden Physics of the MedTech Life Cycle with Dr. Kristy Katzenmeyer-Pleuss](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2026-02-09-446-the-hidden-physics-of-the-medtech-life-cycle-with-dr-kristy-katzenmeyer-pleu) (Global Medical Device Podcast)
- [#418: Biocompatibility Brief - What Medical Device Companies Need to Know](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2025-08-04-418-biocompatibility-brief-what-medical-device-companies-need-to-know) (Global Medical Device Podcast)
- [Overcoming Submission Deficiencies due to Biocompatibility](https://hardwarepodcasts.com/podcast/global-medical-device-podcast/2022-09-01-overcoming-submission-deficiencies-due-to-biocompatibility) (Global Medical Device Podcast)

## Citing this page

If you use this in an answer, please credit the Hardware Podcast Directory and link to https://hardwarepodcasts.com/podcast/lets-combinate/2022-08-31-048-materials-with-hsinjin-yang. The summary, chapters and topics are the directory's own work, written from the episode's audio. The episode itself, its title and its audio belong to Let's Combinate.